The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. The Comfort Suites Simpsonville - Greenville hotel in Simpsonville, SC, will get you refreshed and ready to take on the day for leisure or business. Our all-suites hotel is near Discovery Island Waterpark and the Greenville Zoo. Holly Tree and Fox Run country clubs are nearby. Our 100 percent smoke-free hotel offers complimentary amenities that include free hot breakfast, free WiFi, free weekday newspaper, an indoor pool, exercise room, guest laundry facilities, business center and valet dry cleaning for a fee. Each spacious guest suite features a Flat-Screen TV, hair dryer, coffee maker, desk, microwave, refrigerator, recharge device, iron and ironing board. Also, earn rewards including free nights and gift cards with our Choice Privileges Rewards program.