Behind every great day is a great night at the Comfort Inn South hotel in Indianapolis, IN located off Interstate 465 and U.S. Highway 31. This pet-friendly hotel is located near Indianapolis Zoo, Indianapolis Convention Center, Indiana University-Purdue University Indianapolis, Lucas Oil Stadium and Indianapolis Motor Speedway. Indiana State Museum and Indianapolis Raceway Park are also close. Enjoy amenities like free hot breakfast, free WiFi, news stand, cold weather hook-ups and guest laundry facility. Rooms come equipped with a flat-screen TV and coffee maker. Also, earn rewards including free nights and gift cards with our Choice Privileges Rewards program.