A Pleasant Stay in Prairie du Chien Hotel near Villa Louis and Pikes Peak State Park Enjoy a warm welcome at AmericInn by Wyndham Prairie du Chien, situated on US 18 and WI 35 along Great River Road, a 250 mile national scenic byway. We are close to St. Feriole Island, Villa Louis Historic Site, and Pikes Peak State Park, which is located just over the Iowa border. Shop and dine in charming downtown, try your luck at the nearby Casino Queen Marquette, or go fishing in the Mississippi River or hiking at Pikes Peak State Park, both just a short drive away. For a comfortable stay, our non-smoking hotel offers free breakfast, WiFi, and an indoor pool.