Comfortable, Convenient and Quiet Welcome to the Holiday Inn Express & Suites Mobile – I-65. Our Mobile, Alabama hotel is conveniently located in the heart of the city off I-65 and only minutes from the Mobile Regional Airport (MOB). Our 100% smoke free hotel in Mobile, AL has the amenities to ensure your complete satisfaction. Families and business travelers alike will enjoy.Take advantage of our indoor heated pool and the 24-hour fitness center. All rooms feature a refrigerator and microwave along with a 42in HDTV. Our Holiday Inn Express & Suites Mobile hotel is the perfect place for families in Mobile, AL. Situated in the heart of Mobile, our Alabama hotel offers you easy access to local companies including Austal USA, Alabama Power, EADS Airbus, ThyssenKrupp and the Alabama State Port Authority. Our hotel is convenient to numerous local attractions, including the Mobile Historic District, Exploreum Science Center and the Battleship USS Alabama. Other nearby attractions includes the Robert Trent Jones Golf Trail, Bellingrath Gardens & Home and shopping at the Shoppes of Bel-Air and Legacy Village.Business travelers in Mobile will be impressed by the comfort and amenities of our Holiday Inn Express & Suites Mobile – I-65 hotel. With easy access from I-65 and I-10, our hotel is centrally located near downtown Mobile and the Mobile Regional Airport (MOB). We look forward to seeing you soon.