Enjoy a Comfortable Stay at Our Hotel Near Houston Hobby Airport! Our Houston hotel is perfectly located right off of I45 and Airport Blvd, putting us just minutes from the William P. Hobby Airport. Business travelers looking for a hotel near Texas Medical Center, Port of Houston, IBM, and NASA Johnson Space Center have come to appreciate our hotel in the Houston area. Keep in touch at our 24 hour business center with free Wi-Fi access or take advantage of our meeting space with room for up to 50 guests. Traveling for fun? We are just a short drive from all of the best things to do in Houston. Check out Historic Heights, spend the day exploring the Houston Museum District, and end the day checking out the nightlife in Downtown Houston. Maybe you are planning a trip to Houston to see the Houston Rockets or Houston Astros play. Sports fans love our hotel’s location near Toyota Center, Minute Maid Park, NRG Stadium and the BBVA Compass Stadium. Staying in? Enjoy a dip in our outdoor pool or stay on track with our onsite fitness center. Whether visiting for work or leisure, make it a rewarding stay at the Holiday Inn Express &Suites Houston – Hobby Airport Area.