Nestled in downtown Louisville on historic West Main Street, along Museum Row, 21c Museum Hotel is a multi-venue contemporary art museum, an award-winning 91-room boutique hotel, and home to acclaimed Proof on Main restaurant. Stay with us and the iconic Red Penguin. Wi-Fi internet connection is available for further comfort and convenience. Additionally, the premises provide a reception service the whole day through. Cots are not available at this hotel. 21c Museum Hotel Louisville understands that accessibility is important to all guests. For this reason, it features wheelchair accessible accomodation units and is fully adapted for easy access. 21c Museum Hotel Louisville provides parking for guests' convenience. This hotel has been designed with a conscious effort to adhere to the strictest ecological standards and features the certification.