Off I-270 in Creve Coeur, Holiday Inn St. Louis – Creve Coeur provides easy access to major highways and attractions. Visit the iconic Gateway Arch, catch a Cardinals game at Busch Stadium, explore the St. Louis Zoo, and enjoy performances at the Fox Theatre. Discover the unique exhibits at the City Museum and try your luck at Ameristar or Hollywood casinos. For business travelers, we are conveniently located near Edward Jones, WorldWide Technology, Barnes Jewish Hospital, and Siteman Cancer Center. Host meetings and events in our versatile venue and enjoy top-notch amenities such as a Fitness Center, indoor pool, and onsite restaurant. Unwind in our spacious rooms and suites, ensuring a comfortable stay.