Watertown SD Hotel Near Interstate Welcome to the Holiday Inn Express & Suites hotel in Watertown; located on the corner of Highway 212 and Interstate 29. If you are in town for business, our hotel's great location near this busy intersection keeps you close to all that Watertown SD has to offer. We are in close proximity to Premier Bankcard, Prairie Lakes Healthcare System, and Sparton. You can even host a meeting in one of our two meeting rooms. Families staying at the Watertown Holiday Inn Express can enjoy wonderful attractions near the hotel. Take a visit to the Redlin Art Center, the Bramble Park Zoo, and the Mellette House. Those who enjoy the water will love to spend a day at Lake Kampeska or Pelican Lake. Our hotel even features a great pool area, complete with a 140 ft water slide, three separate themed pools, and a whirlpool. During your visit, we hope you have time to stroll through downtown along Kemp Ave and view over 60 buildings listed on the National Register of Historic Places, and do some shopping at our local stores. After a long day exploring our town, grab a bite to eat at some of the favorite local restaurants including Dempsey's Brewery, Harry's Hair Cuts & Hot Towels, or Minerva's. For those looking to stay close, the Grainery Cafe is located just across the street. We look forward to your stay with us at the Holiday Inn Express Watertown.