21c Museum Hotel Chicago is at the intersection of comfort, culture and curation. A hotel where inspiration is around every corner - dine, entertain and recharge while surrounded by world-class art. Ideally situated one block from Michigan Avenue and within walking distance from popular cultural attractions, 21c Chicago welcomes both visitors and locals to absorb the curated exhibitions, events, and culinary offerings while staying in luxurious accommodations. Come experience the extraordinary. Discover the pinnacle of comfort and culture at 21c Museum Hotel Chicago. Immerse yourself in artistic luxury, dine in style, and relax surrounded by creativity. Ideally located near Michigan Avenue, our hotel offers curated exhibitions and events. 21c Chicago is located just steps from the famous Michigan Avenue Shopping district, Millennium Park, and renowned attractions in downtown Chicago.