Our Walterboro SC Hotel Guests “Stay Smart” Conveniently situated in the heart of the Lowcountry, and newly renovated, this Walterboro, South Carolina hotel is the perfect place to stopover. You'll love exploring downtown's shopping, dining and historic sites and the blackwater rivers and cypress forests surrounding the Holiday Inn Express® Hotel &Suites Walterboro I - 95. Our hotel's corporate guests appreciate our location near some of the area's notable businesses, including the Colleton Medical Center, VA Hospital, Canady's Steam Plant, Dayco Products and Carolina Textile Recycling. Additionally, the free high-speed internet access in every room and a 24-hour business center complement our business-conducive location off I - 95. When our hotel's guests stay in Walterboro, SC, they're an easy drive from Charleston, Savannah and Hilton Head, but there's plenty to do around town, too. Browse the best folk and fine art in the state at the Artisan's Center; take a self-guided historic tour, making sure to stop at the Bedon-Lucas House, the Tuskegee Airmen Monument, and tour the Great Swamp Sanctuary. Join us for a complimentary, hot breakfast every morning. You can get rid of stress in the fitness center after a day of travel or meetings. For an unbeatable location and Lowcountry charm, choose the Holiday Inn Express® Hotel &Suites Walterboro.