The premier hotel in Mattoon, Illinois! Welcome to the Holiday Inn Express Hotel and Suites in Mattoon near Lake Land College and Eastern Illinois University. Our Mattoon, IL hotel is the perfect choice for both corporate & leisure travelers. Families looking for lodging in Mattoon, Illinois will not be disappointed by our hotel, located just off I-57 between Effingham & Champaign. We offer you proximity to many local attractions including the Lincoln Log Cabin State Historic Site, Fox Ridge State Park, and the Douglas-Hart Nature Center. Other nearby activities include Lake Mattoon, Lake Shelbyville (11,000 Acres of Water), Rockome Gardens, and shopping at the Tanger Outlet Mall. Business travelers will be impressed by the convenience of our Mattoon, IL accommodations. Situated in a suburban area of Mattoon, Illinois, the hotel is close to several companies including Hydro Incorporated, Mediacom, Bimbo Bakeries, Rural King, Sarah Bush Lincoln Medical Center, and the Mattoon Softball Complex. In addition, we provide a business center with a fax machine, printer, copier, public computer, and free high-speed, wired and wireless Internet access. While staying in Illinois, you can enjoy our choice hotel amenities which include a 24-hour fitness center, heated indoor pool, spa and complimentary breakfast. Book now to enjoy our great Mattoon, IL hotel deals and rates. Limited ADA rooms on first floor. Please call hotel for ADA information.