Stay at Holiday Inn Express® & Suites Wharton Hotel Welcome to Wharton, a friendly Texas town full of history, businesses and antique shopping. Staying at our Wharton hotel means that you can enjoy a slower, more peaceful pace while still having convenient access to the metropolitan Houston area. You can find us off Hwy 59 next to the South Texas Medical Clinic and the Gulf Coast Medical Center. Our Wharton hotel understands that corporate travelers need certain amenities to stay ahead of the game. That is why we offer a 24-hour Business Center featuring high-speed Internet access. In addition, we are located close to area businesses, such as Nanya Plastics and J-M Manufacturing. Leisure travelers love our hotel's property in Wharton because of its close proximity to exciting area attractions. Choose from activities like spending the day at top bird hunting areas, learning the culture of the region at the Wharton County Historical Museum or visiting a student at the junior college. We are close enough to Houston for you to take a quick day trip into the city. If you are looking for hotels in Wharton with choice amenities, consider ours. We feature free, high-speed Internet access in all public areas, a complimentary, hot Express Start Breakfast Bar, a huge outdoor pool and a well-equipped Fitness Center. Here at the Holiday Inn Express® & Suites Wharton hotel, we look forward to serving you!