The Quality Inn Cairo I-57 hotel in Cairo, IL gives you more for your money when corporate travel sends you to the southern tip of Illinois. Our hotel is situated right off Interstate 57 providing you easy access to neighboring states Missouri and Kentucky. Our value is to deliver professional, responsive and friendly service, as well as amenities like a free hot breakfast, free WiFi, an outdoor pool and access to business services. Plus, each guest room offer premium bedding, microwave, refrigerator, hair dryer and flat-screen TV. Also, earn rewards including free nights and gift cards with our Choice Privileges Rewards program.